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Medical Wiki

Alanine aminotransferase (ALT)

A liver enzyme often used in liver-panel context for liver-cell injury.

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What it is

ALT is an enzyme included in liver function testing.^[1,2]

Why it matters

Higher ALT can enter liver-cell injury discussions, but it does not diagnose a specific liver disease by itself.^[1,2]

What it affects

ALT is often read with AST, bilirubin, alkaline phosphatase, albumin, history, and imaging context.^[1,2]

Interpretation traps

A normal or abnormal ALT alone is not a diagnosis or treatment decision.^[1,2]

Related conditions

Fatty liver disease and steatosis Viral hepatitis and liver inflammation