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Serum creatinine

A muscle-waste product measured in blood and used to estimate kidney filtration.

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What it is

Creatinine is a waste product from muscle activity that kidneys remove from blood.^[1,2]

Why it matters

Blood creatinine is often used to estimate eGFR, but creatinine alone is not the best kidney-function measure.^[1,2]

What it affects

Creatinine depends on muscle mass, diet, age, activity, and clinical context.^[1,2]

Interpretation traps

A single high creatinine result cannot diagnose a specific condition.^[1,2]

Related conditions

Chronic kidney disease and filtration loss Acute kidney injury and sudden function loss Kidney failure and replacement-therapy context